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Rambler's Top100

Поддержка сайта - студия "Сертификат публикации"

  Elena V. Eremeeva

Elena V. Eremeeva

Laboratory of Photobiology

Institute of Biophysics

Akademgorodok 660036 Krasnoyarsk Russia

Tel: (3912) 494430

E-mail: l_eremeeva@mail.ru

EDUCATIONAL BACKGROUND

  • Ph.D. thesis Molecular mechanism of active photoprotein complex formation

  • 2013 Ph.D., Biochemistry, Wageningen University, Wageningen, The Netherlands

  • 2010 Ph.D., Biophysics, Krasnoyarsk State University, Krasnoyarsk, Russia

  • 2005 M.Sc., Biochemistry, Krasnoyarsk State University, Krasnoyarsk, Russia

PROFESSIONAL EXPERIENCE

  • 2008-present Laboratory of Photobiology, Institute of Biophysics SB RAS, research scientists (2012-present), junior research scientist (2008-2012)

INTERNATIONAL PROFESSIONAL TRAVEL

  • 2012-2013 (August-January) Collaborative research funded by Sandwich PhD fellowship, Wageningen University, Wageningen, The Netherlands

  • 2011 (March-July) Collaborative research funded by Sandwich PhD fellowship, Wageningen University, Wageningen, The Netherlands

  • 2010 (October-December) Collaborative research, the National Lab of Biomacromolecules, Institute of Biophysics, Beijing, China

  • 2009 (April-June) Collaborative research, the National Lab of Biomacromolecules, Institute of Biophysics, Beijing, China

  • 2007 (February-September) Collaborative research funded by Sandwich PhD fellowship, Wageningen University, Wageningen, The Netherlands

INTERNATIONAL CONFERENCES/SEMINARS ATTENDED

  • 2016 19th Int. Symposium on Bioluminescence and Chemiluminescence, Tsukuba, Japan

  • 2014 18th International Symposium on Flavins and Flavoproteins, Cha-Am, Thailand

  • 2012 NWO Study Group Meeting Biomolecular Chemistry, Lunteren, The Netherlands

  • 2012 17th Int. Symposium on Bioluminescence and Chemiluminescence, Guelph, Canada

  • 2010 35th FEBS Congress, Gothenburg, Sweden

  • 2008 15th Int. Symposium on Bioluminescence and Chemiluminescence, Shanghai, China, winner of Marlene DeLuca Prize for young scientists.

PUBLICATIONS

PAPERS IN PEER REVIEWD JOURNALS

  • Burakova L.P., Natashin P.V., Markova S.V., Eremeeva E.V., Malikova N.P., Cheng C., Liu Z.J., Vysotski E.S. (2016) Mitrocomin from the jellyfish Mitrocoma cellularia with deleted C-terminal tyrosine reveals a higher bioluminescence activity compared to wild type photoprotein. J Photochem Photobiol B., 162, 286-297.

  • Burakova L.P., Stepanyuk G.A., Eremeeva E.V., Vysotski E.S. (2016) Role of certain amino acid residues of the coelenterazine-binding cavity in bioluminescence of light-sensitive Ca(2+)-regulated photoprotein berovin. Photochem Photobiol Sci., 15, 691-704.

  • Eremeeva E.V., van Berkel W.J., Vysotski E.S. (2016) Transient-state kinetic analysis of complex formation between photoprotein clytin and GFP from jellyfish Clytia gregaria. FEBS Lett., 590, 307-316.

  • Natashin P.V., Ding W., Eremeeva E.V., Markova S.V., Lee J., Vysotski E.S., Liu Z.-J. (2014) Structures of the Ca2+-regulated photoprotein obelin Y138F mutant before and after bioluminescence support the catalytic function of a water molecule in the reaction. Acta Crystallogr. D Biol. Crystallogr., 70, 720–732

  • Eremeeva E.V., Burakova L.P., Krasitskaya V.V., Kudryavtsev A.N., Shimomura O., Frank L.A. (2014) Hydrogen-bond networks between the C-terminus and Arg from the first a-helix stabilize photoprotein molecules. Photochem. Photobiol. Sci., 13, 541-547.

  • Eremeeva E.V., Markova S.V., van Berkel W.J.H., Vysotski E.S. (2013) Role of key residues of obelin in coelenterazine binding and conversion into 2-hydroperoxy adduct. J. Photochem. Photobiol. B, 127, 133-139.

  • Eremeeva, E.V., Markova, S.V., Vysotski, E.S. (2013) Highly active BRET-reporter based on yellow mutant of Renilla muelleri luciferase. Dokl. Biochem. Biophys., 450, 147-150.

  • Eremeeva, E.V., Natashin, P.V., Song, L., Zhou, Y.G., van Berkel, W.J.H., Liu, Z.J, Vysotski, E.S. (2013) Oxygen activation of apo-obelin-coelenterazine complex. Chembiochem., 14, 739-745.

  • Eremeeva, E.V., Markova, S.V., Frank, L.A., Visser, A.J.W.G., van Berkel, W.J.H., Vysotski, E.S. (2013) Bioluminescent and spectroscopic properties of His-Trp-Tyr triad mutants of obelin and aequorin. Photoch. Photobio. Sci., 12, 1016-1024.

  • Eremeeva, E.V., Vysotski, E.S., Westphal, A.H., van Mierlo, C.P.M., van Berkel, W.J.H. (2012) Ligand binding and conformational states of the photoprotein obelin. FEBS Lett., 586, 4173–4179.

  • Eremeeva, E.V., Frank, L.A., Markova S.V., Vysotski, E.S. (2010) Ca2+-regulated photoprotein obelin as N-terminal partner in the fusion proteins. Journal of Siberian Federal University, B4, 372-383.

  • van Oort, B., Eremeeva, E.V., Koehorst, R.B.M., Laptenok, S.P., van Amerongen, H., van Berkel, W.J.H., Malikova, N.P., Markova, S.V., Vysotski, E.S., Visser, A.J.W.G., Lee, J. (2009) Picosecond fluorescence relaxation spectroscopy of the calcium-discharged photoproteins aequorin and obelin. Biochemistry, 48, 10486-10491.

  • Eremeeva, E.V., Markova, S.V., Westphal, A.H., Visser, A.J.W.G., van Berkel, W.J.H., Vysotski, E.S. (2009) The intrinsic fluorescence of apo-obelin and apo-aequorin and use of its quenching to characterize coelenterazine binding. FEBS Lett., 583, 1939-1944.

MONOGRAPH

  • Eremeeva E.V. Molecular mechanism of active photoprotein complex formation. Print Service Ede, The Netherlands, 2013, 195 pages. ISBN 978-94-6173-458-7.