Pavel V. Natashin

Date of birth: June 1, 1988

Place of birth: Krasnoyarsk, Russia

Nationality: Russia

Educational background:

• High School #1, Zykovo, Krasnoyarskij kraj, Russia. High School Diploma (2005)

• Siberian Federal University, Institute of Fundamental Biology and biotechnology

  Chair of Medical Biology, Krasnoyarsk, Russia.

  M.S. in Biochemistry (2010)

  (Experimental studies on getting M.S. in biochemistry were carried out in the laboratory of photobiology at the Institute of Biophysics Russian Academy of Sciences Siberian Branch, Krasnoyarsk, Russia in 2007 – 2010. MS advisor: Dr. S.V. Markova.)

• Siberian Federal University, Institute of Fundamental Biology and biotechnology,

  Chair of Biophysics, Krasnoyarsk, Russia. PhD in Biophysics (2014)

  (Experimental studies are being carried out in the laboratory of photobiology at the Institute of Biophysics Russian Academy of Sciences Siberian Branch, Krasnoyarsk, Russia and in the National laboratory of biomacromolecules at the Institute of Biophysics Chinese Academy of Sciences, Beijing, China. PhD advisor: Prof. E.S. Vysotski, head of the laboratory of photobiology.)

Professional appointments:

• Junior Research Scientist of Photobiology Lab

  Institute of Biophysics SB RAS, Krasnoyarsk, Russia From 2012

• Joint PhD student of National Lab of Biomacromolecules

  Institute of Biophysics CAS, Beijing, China. 2010–2013

• Assistant of Photobiology Lab

  Institute of Biophysics SB RAS, Krasnoyarsk, Russia. 2009–2012

Publications:

1. Burakova L.P., Natashin P.V., Markova S.V., Eremeeva E.V., Malikova N.P., Cheng C. Liu Z.J., Vysotski E.S. (2016) Mitrocomin from the jellyfish Mitrocomacellularia with deleted C-terminal tyrosine reveals a higher bioluminescence activity compared to wild type photoprotein. J PhotochemPhotobiol B. 162:286-297.

2. Burakova L.P., Natashin P.V., Malikova N.P., Niu F., Pu M., Vysotski E.S., Liu Z.J. (2016) All Ca(2+)-binding loops of light-sensitive ctenophore photoproteinberovin bind magnesium ions: The spatial structure of Mg(2+)-loaded apo-berovin. J PhotochemPhotobiol B. 154:57-66.

3. Natashin P.V., Ding W., Eremeeva E.V., Markova S.V., Lee J., Vysotski E.S., Liu Z.J. (2014) Structures of the Ca(2+)-regulated photoprotein obelin Y138F mutant before and after bioluminescence support the catalytic function of a water molecule in the reaction. Acta Crystallographica Section D 70:720-732.

4. Natashin P.V., Markova S.V., Lee J., Vysotski E.S., Liu Z.J. (2014) Crystal structures of the F88Y obelin mutant before and after bioluminescence provide molecular insight into spectral tuning among hydromedusan photoproteins. FEBS Journal 281:1432-1445.

5. Eremeeva E.V., Natashin P.V., Song L., Zhou Y., van Berkel W.J., Liu Z.J., and Vysotski E.S. (2013) Oxygen activation of apo-obelin-coelenterazine complex. ChemBioChem 14:739-745.

6. Natashin, P.V. (2010) Photoprotein obelin as bioluminescent marker for fragment-complementation analysis of protein–protein interactions. Proc. XLVIII International Students Scientific Conference “A student and scientific and technical progress”, Novosibirsk, 85-86. (In Russian).